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CasNo: 117928-94-6
Molecular Formula: C18H31N5O6
Buy Good Quality GLYX 13 117928-94-6 with a minimum purity of 99% We supply high quality GLYX 13 (CAS 117928-94-6), in stock, factory directly supply to clients, lower prices, more competitiveness.
GLYX 13 is , while it's Molecular Formula is C18H31N5O6. GLYX-13 trifluoroacetate has been used as an activator of NMDA (N-methyl-D-aspartate) receptor.
The CAS number of GLYX 13 is 117928-94-6.
More information of GLYX 13 117928-94-6 are:
Synonyms |
GLYX 13 |
CAS Number |
117928-94-6 |
Molecular Formula |
C18H31N5O6 |
Molecular Weight |
413.474 |
Density |
1.37 g/cm3 |
Boiling Point |
844.212 °C at 760 mmHg |
Flash Point |
464.363 °C |
PSA |
179.29000 |
LogP |
-1.30530 |
Pka |
12.26±0.45(Predicted) |
GLYX 13, also known as Rapastinel, is an investigational drug developed as a novel antidepressant for the treatment of depressive disorders, particularly major depressive disorder. It is a centrally active, intravenously administered amidated tetrapeptide (Thr-Pro-Pro-Thr-NH2) that acts as a selective, weak partial agonist (mixed antagonist/agonist) of an allosteric site at the glycine site of the NMDA receptor complex (Emax ≈ 25%). GLYX 13 is characterized by its rapid-acting and long-lasting antidepressant effects, as well as its robust cognitive enhancement capabilities due to its ability to both inhibit and enhance NMDA receptor-mediated signal transduction.
Articles related to GLYX 13:
Article |
Source |
Scale-Up synthesis and identification of GLYX-13, a NMDAR glycine-site partial agonist for the treatment of major depressive disorder |
Li, Wenchao,Liu, Jingjian,Fan, Minghua,Li, Zhongtang,Chen, Yin,Zhang, Guisen,Huang, Zhuo,Zhang, Liangren , (2018) |
PROCESS AND INTERMEDIATES FOR SYNTHESIS OF PEPTIDE COMPOUNDS |
- , (2019/02/13) |
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