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GLYX 13

  • Product Name: GLYX 13
  • CasNo: 117928-94-6
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CasNo: 117928-94-6

Molecular Formula: C18H31N5O6

Buy Good Quality GLYX 13 117928-94-6 with a minimum purity of 99% We supply high quality GLYX 13 (CAS 117928-94-6), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the GLYX 13 ?

GLYX 13 is , while it's Molecular Formula is C18H31N5O6. GLYX-13 trifluoroacetate has been used as an activator of NMDA (N-methyl-D-aspartate) receptor.

What is the CAS number for GLYX 13 ?

The CAS number of GLYX 13 is 117928-94-6.

More information of GLYX 13 117928-94-6 are:

Synonyms

GLYX 13

CAS Number

117928-94-6

Molecular Formula

C18H31N5O6

Molecular Weight

413.474

Density

1.37 g/cm3

Boiling Point

844.212 °C at 760 mmHg

Flash Point

464.363 °C

PSA

179.29000

LogP

-1.30530

Pka

12.26±0.45(Predicted)

What is GLYX 13 (117928-94-6) used for?

GLYX 13, also known as Rapastinel, is an investigational drug developed as a novel antidepressant for the treatment of depressive disorders, particularly major depressive disorder. It is a centrally active, intravenously administered amidated tetrapeptide (Thr-Pro-Pro-Thr-NH2) that acts as a selective, weak partial agonist (mixed antagonist/agonist) of an allosteric site at the glycine site of the NMDA receptor complex (Emax ≈ 25%). GLYX 13 is characterized by its rapid-acting and long-lasting antidepressant effects, as well as its robust cognitive enhancement capabilities due to its ability to both inhibit and enhance NMDA receptor-mediated signal transduction.

Articles related to GLYX 13:

Article

Source

Scale-Up synthesis and identification of GLYX-13, a NMDAR glycine-site partial agonist for the treatment of major depressive disorder

Li, Wenchao,Liu, Jingjian,Fan, Minghua,Li, Zhongtang,Chen, Yin,Zhang, Guisen,Huang, Zhuo,Zhang, Liangren

, (2018)

PROCESS AND INTERMEDIATES FOR SYNTHESIS OF PEPTIDE COMPOUNDS

-

, (2019/02/13)

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