Mobile/Wechat/WhatsApp: +447394406898
Email:wibson.aris@gmail.com
CasNo: 1071-83-6
Molecular Formula: C3H8NO5P
Appearance: white powder
Description |
Glyphosate, [N-(phosphonomethyl) glycine], was synthesized in 1950 and patented as a chemical chelator, capable of binding metals such as calcium, magnesium, and manganese. Shanghai Wibson Biotechnology Co., Ltd. is a high-tech enterprise that mainly develops and sells pharmaceutical and chemical raw materials and other related products. We have 16 years of experience in R&D and manufacturing, we have rich experience in shipping, many well-known companies have cooperated with us, and are good at shipping various chemical products with us.We can provide OEM,ODM service with low MOQ! |
Uses |
Glyphosate is an active ingredient (a.i.) in very widely used herbicide formulations. Accordingly, the toxicity of glyphosate and glyphosate-based formulations (GBFs) has been extensively studied. Glyphosate is absorbed through plant leaves. It is then carried by the sap stream into the plant roots, where it prevents them from absorbing nutrients from the soil – thereby killing the plant. Annual weeds, including grasses and most broad-leafed plants, are easily controlled using Glyphosate. |
Toxicity |
Acute oral-rat LD50 is 4320mg/kg, acute percutaneous-rabbit LD50> 5000mg/kg (7940mg/kg); it has mild stimulus on skin and eyes of rabbits. Using a dose 2000 mg/kg for feeding rats for 90d causes no abnormal symptoms. Animal tests exhibit no teratogenic, carcinogenic, mutagenic effect. Trout-LC50> 1000mg/L, Daphnia 780mg/L. It has low toxicity to bees and birds. |
Flammability and hazard characteristics |
combustion produces toxic gases of nitrogen oxides and phosphorus oxides |
Storage characteristics |
Treasury: ventilation, low-temperature and drying; store separately from food raw material |
Extinguishing agent |
Dry powder, foam, sand |
Reactivity Profile |
Glyphosate may react with galvanized steel or unlined steel (except stainless steel) containers to produce hydrogen gas which may form a highly combustible or explosive gas mixture. Glyphosate can react with caustic (basic) materials to liberate heat. Glyphosate is corrosive to iron. |
Fire Hazard |
Flash point data for Glyphosate are not available; however, Glyphosate is probably combustible. |
Biochem/physiol Actions |
Glyphosate?(N-[phosphonomethyl] glycine) is the herbicide form of the isopropylamine salt of glyphosate. |
Potential Exposure |
A potential danger to those involved in the manufacture, formulation, and application of this nonselective and nonresidual pre-emergence organophos phate herbicide. Has wide residential use in the United States for the control of weeds. |
Metabolic pathway |
The photolytic degradation of glyphosate results in the formation of glycine, (aminomethyl)phosphonic acid (AMPA), and NH3. Glyphosate undergoes nitrogen ? carbon cleavage on reaction with m- chloroperoxybenzoic acid, leading ultimately to many of the same products formed on their metabolism and environmental degradation. It is suggested that insoluble complexes of glyphosate with iron(III), copper(II), calcium, and magnesium ions are formed at near-neutral pH, a mechanism of which is the inactivation of glyphosate in contaminated groundwater.268 The bacterium degrades high levels of glyphosate, primarily by converting to AMPA. Appreciable uptake of glyphosate is observed with seedlings and leaves and to a lesser extent with culture cells in the form of non-metabolized glyphosate, with AMPA as the only detectable metabolite. |
Metabolism |
In soils, glyphosate is rapidly mineralized within 1 to 2 weeks, and degradation occurs under aerobic and anaerobic conditions (79). The C?P bond is relatively resistant to chemical degradation, but several bacteria, e.g., Arthrobacter (80), Pseudomonas (81), various members of the Rhizobiaceae family (82), and certain fungi (83), have been shown to metabolize glyphosate. |
Shipping |
UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz ardous material, Technical Name Required. |
InChI:InChI=1/C3H6NO5P/c5-3(6)1-4-2-10(7,8)9/h1H,2H2,(H,5,6)(H2,7,8,9)
Glyphosate and glyphosate-resistant crops had a revolutionary impact on weed management practices, but the epidemic of glyphosate-resistant (GR) weeds is rapidly decreasing the value of these technologies. In areas that fully adopted glyphosate and GR crops, GR weeds evolved and glyphosate and glyphosate traits now must be combined with other technologies.
Although Monsanto’s patent on glyphosate expired in 2002, the widespread and growing use of Roundup Ready™ seed globally and competitive glyphosate marketing by other chemical companies have led to glyphosate’s significant increase in the environment. Concerns about potential adverse effects have also grown.
An x-ray structural study of phosphonome...
An earlier extensive review of glyphosate and glyphosate formulation safety and risk assessment included descriptions and analyses of genetic toxicology studies of glyphosate and Roundup™-branded and other glyphosate formulations
methyl phosphite
N-(phosphonemethyl)glycine
Conditions | Yield |
---|---|
|
|
|
|
|
phosphonomethylimino-di-acetic acid
formaldehyd
formic acid
Aminomethylphosphonic acid
N-methylaminomethanephosphonic acid
N-methyl N-phosphonomethylglycine
N-(phosphonemethyl)glycine
Phosphate
Conditions | Yield |
---|---|
With oxygen; In water; at 100 ℃; Reagent/catalyst; Flow reactor;
|
dibutyl hydrogen phosphite
phosphonomethylimino-di-acetic acid
N-phosphonomethyl-glycine ethyl ester
N-<(diethoxyphosphonyl)methyl>glycine ethyl ester
D-mannitol 6-phosphate
ammonium glyphosate
tri-sodium salt of N-phosphonomethylglycine
Mono-tetraphenylphosphonium Salt of N-Phosphonomethylglycine