Pharmaceutical raw materials

Home - Products - Pharmaceutical raw materials

Glyphosate

  • Product Name: Glyphosate
  • CasNo: 1071-83-6
  • Purity:
  • Appearance: white powder

Mobile/Wechat/WhatsApp: +447394406898

Email:wibson.aris@gmail.com

Inquiry

CasNo: 1071-83-6

Molecular Formula: C3H8NO5P

Appearance: white powder

Quality Factory Supply 99% Pure Glyphosate 1071-83-6 with Efficient Delivery

  • Molecular Formula:C3H8NO5P
  • Molecular Weight:169.074
  • Appearance/Colour:white powder 
  • Melting Point:230 °C 
  • Refractive Index:1.576 
  • Boiling Point:465.8 °C at 760 mmHg 
  • PKA:1.22±0.10(Predicted) 
  • Flash Point:235.5 °C 
  • PSA:116.67000 
  • Density:1.679 g/cm3 
  • LogP:-0.81330 

Glyphosate(Cas 1071-83-6) Usage and Factory

Description

Glyphosate, [N-(phosphonomethyl) glycine], was synthesized in 1950 and patented as a chemical chelator, capable of binding metals such as calcium, magnesium, and manganese. Shanghai Wibson Biotechnology Co., Ltd. is a high-tech enterprise that mainly develops and sells pharmaceutical and chemical raw materials and other related products. We have 16 years of experience in R&D and manufacturing, we have rich experience in shipping, many well-known companies have cooperated with us, and are good at shipping various chemical products with us.We can provide OEM,ODM service with low MOQ!

Uses

Glyphosate is an active ingredient (a.i.) in very widely used herbicide formulations. Accordingly, the toxicity of glyphosate and glyphosate-based formulations (GBFs) has been extensively studied. Glyphosate is absorbed through plant leaves. It is then carried by the sap stream into the plant roots, where it prevents them from absorbing nutrients from the soil – thereby killing the plant. Annual weeds, including grasses and most broad-leafed plants, are easily controlled using Glyphosate.

Toxicity

Acute oral-rat LD50 is 4320mg/kg, acute percutaneous-rabbit LD50> 5000mg/kg (7940mg/kg); it has mild stimulus on skin and eyes of rabbits. Using a dose 2000 mg/kg for feeding rats for 90d causes no abnormal symptoms. Animal tests exhibit no teratogenic, carcinogenic, mutagenic effect. Trout-LC50> 1000mg/L, Daphnia 780mg/L. It has low toxicity to bees and birds.

Flammability and hazard characteristics

combustion produces toxic gases of nitrogen oxides and phosphorus oxides

Storage characteristics

Treasury: ventilation, low-temperature and drying; store separately from food raw material

Extinguishing agent

Dry powder, foam, sand

Reactivity Profile

Glyphosate may react with galvanized steel or unlined steel (except stainless steel) containers to produce hydrogen gas which may form a highly combustible or explosive gas mixture. Glyphosate can react with caustic (basic) materials to liberate heat. Glyphosate is corrosive to iron.

Fire Hazard

Flash point data for Glyphosate are not available; however, Glyphosate is probably combustible.

Biochem/physiol Actions

Glyphosate?(N-[phosphonomethyl] glycine) is the herbicide form of the isopropylamine salt of glyphosate.

Potential Exposure

A potential danger to those involved in the manufacture, formulation, and application of this nonselective and nonresidual pre-emergence organophos phate herbicide. Has wide residential use in the United States for the control of weeds.

Metabolic pathway

The photolytic degradation of glyphosate results in the formation of glycine, (aminomethyl)phosphonic acid (AMPA), and NH3. Glyphosate undergoes nitrogen ? carbon cleavage on reaction with m- chloroperoxybenzoic acid, leading ultimately to many of the same products formed on their metabolism and environmental degradation. It is suggested that insoluble complexes of glyphosate with iron(III), copper(II), calcium, and magnesium ions are formed at near-neutral pH, a mechanism of which is the inactivation of glyphosate in contaminated groundwater.268 The bacterium degrades high levels of glyphosate, primarily by converting to AMPA. Appreciable uptake of glyphosate is observed with seedlings and leaves and to a lesser extent with culture cells in the form of non-metabolized glyphosate, with AMPA as the only detectable metabolite.

Metabolism

In soils, glyphosate is rapidly mineralized within 1 to 2 weeks, and degradation occurs under aerobic and anaerobic conditions (79). The C?P bond is relatively resistant to chemical degradation, but several bacteria, e.g., Arthrobacter (80), Pseudomonas (81), various members of the Rhizobiaceae family (82), and certain fungi (83), have been shown to metabolize glyphosate.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz ardous material, Technical Name Required.

InChI:InChI=1/C3H6NO5P/c5-3(6)1-4-2-10(7,8)9/h1H,2H2,(H,5,6)(H2,7,8,9)

1071-83-6 Relevant articles

The rise and future of glyphosate and glyphosate-resistant crops

Jerry M Green

, Pest management science, Volume74, Issue5 Special Issue:Glyphosate May 2018 Pages 1035-1039

Glyphosate and glyphosate-resistant crops had a revolutionary impact on weed management practices, but the epidemic of glyphosate-resistant (GR) weeds is rapidly decreasing the value of these technologies. In areas that fully adopted glyphosate and GR crops, GR weeds evolved and glyphosate and glyphosate traits now must be combined with other technologies.

Glyphosate: A review of its global use, environmental impact, and potential health effects on humans and other species

Martha E. Richmond

, Journal of Environmental Studies and Sciences, Volume 8, pages 416–434, (2018)

Although Monsanto’s patent on glyphosate expired in 2002, the widespread and growing use of Roundup Ready™ seed globally and competitive glyphosate marketing by other chemical companies have led to glyphosate’s significant increase in the environment. Concerns about potential adverse effects have also grown.

X-RAY STRUCTURAL STUDY OF ORGANIC LIGANDS OF THE COMPLEXONE TYPE. III. CRYSTAL AND MOLECULAR STRUCTURE OF PHOSPHONOMETHYLGLYCINE AND IMINODIACETIC-MONOMETHYLPHOSPHONIC ACID

Shkol'nikova, L. M.,Porai-Koshits, M. A.,Dyatlova, N. M.,Yaroshenko, G. F.,Rudomino, M. V.,Kolova, E. K.

, p. 737 - 746 (1982)

An x-ray structural study of phosphonome...

Review of genotoxicity studies of glyphosate and glyphosate-based formulations

Larry D. Kier &David J. Kirkland

, Critical Reviews in Toxicology Volume 43, 2013 - Issue 4

An earlier extensive review of glyphosate and glyphosate formulation safety and risk assessment included descriptions and analyses of genetic toxicology studies of glyphosate and Roundup™-branded and other glyphosate formulations

1071-83-6 Process route

methyl phosphite
96-36-6,868-85-9

methyl phosphite

N-(phosphonemethyl)glycine
1071-83-6

N-(phosphonemethyl)glycine

Conditions
Conditions Yield
 
 
 
 
 
 
phosphonomethylimino-di-acetic acid
5994-61-6

phosphonomethylimino-di-acetic acid

formaldehyd
50-00-0,30525-89-4,61233-19-0

formaldehyd

formic acid
64-18-6

formic acid

Aminomethylphosphonic acid
1066-51-9

Aminomethylphosphonic acid

N-methylaminomethanephosphonic acid
35404-71-8

N-methylaminomethanephosphonic acid

N-methyl N-phosphonomethylglycine
24569-83-3

N-methyl N-phosphonomethylglycine

N-(phosphonemethyl)glycine
1071-83-6

N-(phosphonemethyl)glycine

Phosphate
14265-44-2,264888-19-9

Phosphate

Conditions
Conditions Yield
With oxygen; In water; at 100 ℃; Reagent/catalyst; Flow reactor;
 

1071-83-6 Upstream products

  • 1809-19-4
    1809-19-4

    dibutyl hydrogen phosphite

  • 5994-61-6
    5994-61-6

    phosphonomethylimino-di-acetic acid

  • 39600-47-0
    39600-47-0

    N-phosphonomethyl-glycine ethyl ester

  • 60711-71-9
    60711-71-9

    N-<(diethoxyphosphonyl)methyl>glycine ethyl ester

1071-83-6 Downstream products

  • 13270-18-3
    13270-18-3

    D-mannitol 6-phosphate

  • 69254-40-6
    69254-40-6

    ammonium glyphosate

  • 34494-03-6
    34494-03-6

    tri-sodium salt of N-phosphonomethylglycine

  • 83591-41-7
    83591-41-7

    Mono-tetraphenylphosphonium Salt of N-Phosphonomethylglycine

Leave Your Message

Relevant Products