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- Molecular Formula:C16H34O
- Molecular Weight:242.445
- Appearance/Colour:white solid
- Vapor Pressure:<0.01 mm Hg ( 43 °C)
- Melting Point:49-51 °C
- Refractive Index:nD79 1.4283
- Boiling Point:310.9 °C at 760 mmHg
- PKA:15.20±0.10(Predicted)
- Flash Point:135 °C
- PSA：20.23000
- Density:0.818 g/cm3
- LogP:5.46000
- IDLH:114
- IDLH:57
- IDLH:2554
Palmitol(Cas 36653-82-4) Usage
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Description
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Palmitol is a C-16 fatty alcohol. At room temperature, cetyl alcohol takes the form of a waxy white solid or flakes. |
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Flammability and Explosibility
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Notclassified
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Uses
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Palmitol is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions. |
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Incompatibilities
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Incompatible with strong oxidizing agents. Cetyl alcohol is responsible for lowering the melting point of ibuprofen, which results in sticking tendencies during the process of film coating ibuprofen crystals.
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Regulatory Status
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Included in the FDA Inactive Ingredients Database (ophthalmic preparations, oral capsules and tablets, otic and rectal preparations, topical aerosols, creams, emulsions, ointments and solutions, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Nonmedicinal Ingredients.
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Who Evaluation
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Evaluation year: 1997
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InChI:InChI=1/C16H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h17H,2-16H2,1H3
36653-82-4 Relevant articles
Effect of cetostearyl alcohol on stabilization of oil-in-water emulsion: I. Difference in the effect by mixing cetyl alcohol with stearyl alcohol
S Fukushima, M Takahashi, M Yamaguchi
Journal of Colloid and Interface Science Volume 57, Issue 2, November 1976, Pages 201-206
It is known that an oil-in-water emulsion increases in consistency and stability on addition of cetostearyl alcohol. When either cetyl alcohol or stearyl alcohol was added individually, the emulsion stability decreased. On storage at room temperature, unstable emulsions decreased in consistency and many particles (not visible immediately after preparation) appeared. The particles were determined to be crystals of the alcohol added. When both alcohols were included in the formulation simultaneously in the appropriate ratio, the emulsions were stable and did not show such changes. This difference in stability can be explained in relation to polymorphism of the alcohols.
Discovery of Anti-TNBC Agents Targeting PTP1B: Total Synthesis, Structure-Activity Relationship, in Vitro and in Vivo Investigations of Jamunones
Hu, Caijuan,Li, Guoxun,Mu, Yu,Wu, Wenxi,Cao, Bixuan,Wang, Zixuan,Yu, Hainan,Guan, Peipei,Han, Li,Li, Liya,Huang, Xueshi
supporting information, p. 6008 - 6020 (2021/05/06)
Twenty-three natural jamunone analogues ...
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