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CasNo: 7683-64-9
Molecular Formula: C30H50
Appearance: light yellow liquid
Description | Squalene is a natural triterpene and an important intermediate of sterol and hopanoid biosynthesis in various types of cell from bacteria to human. |
Uses |
Squalane, a saturated oil that's used in skin care products as a moisturizer, helps increase hydration, and thanks to its anti-inflammatory properties, can help with acne and eczema. |
InChI:InChI=1/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+
Shanghai Wibson Biotechnology Co., Ltd. is a high-tech enterprise that mainly develops and sells pharmaceutical and chemical raw materials and other related products. The company has advanced and perfect supporting system and has formed advanced chemical synthesis technology, which can quickly meet the personalized needs and series development from suitable testing to industrial production. Products are exported to Russia, Southeast Asia and other countries, in the world has a very high reputation and visibility. The company has strong financial strength and a good operating environment, can provide customers with high-quality, efficient and fast services.
Synthesis and further conversion of squalene are key steps in the metabolism of sterols and related components. Here we summarize the recent knowledge of squalene biochemistry, its molecular properties, and its physiological effects. We compare squalene biosynthetic pathways in different cell types and describe biotechnological strategies to isolate this lipid. Finally, applications of squalene in nutrition, pharmacy, and medicine are discussed.
On the basis of the presented reports, squalene and squalane are two naturally derived compounds with bright future in nutraceutical and pharmaceutical area. Squalene, which can be obtained by natural sources, exists readily in human body and yet to be examined in detail for its biological role.
Farnesol
(6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyl-tetracosa-2,6,10,14,18,22-hexaene
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps
1: 60 percent / methanesulfonyl chloride, pyridine / pentane
2: 1.) Pd2(dba)3CHCl3 / 1.) benzene; 2.) irradiation, acetonitrile
With pyridine; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; methanesulfonyl chloride; In pentane;
|
1-chloro-3,7,11-trimethyldodeca-2,6,10-triene
(6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyl-tetracosa-2,6,10,14,18,22-hexaene
Conditions | Yield |
---|---|
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; Multistep reaction; 1.) benzene; 2.) irradiation, acetonitrile;
|
1-chloro-3,7,11-trimethyldodeca-2,6,10-triene
(2E,6E)-farnesyl chloride
Farnesol
2,6,10,15,19,23-hexamethyltetracosane