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What is the Chlorpheniramine maleate ?
Chlorpheniramine maleate is White crystalline powder, while it's Molecular Formula is C20H23ClN2O4. Chlorphenamine is an antihistamine medicine that relieves the symptoms of allergies. It's known as a drowsy (sedating) antihistamine. This means that it is likely to make you feel more sleepy than some other antihistamines. It's used for: hay fever.
What is the CAS number for Chlorpheniramine maleate ?
The CAS number of Chlorpheniramine maleate is 113-92-8.
More information of Chlorpheniramine maleate 113-92-8 are:
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Synonyms
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2-Pyridinepropanamine,?-(4-chlorophenyl)-N,N-dimethyl- [132-22-9] but the (Z)-2-butenedioate (1:1);Prestwick_57;Allergin;Chlor-trimeton;Teldrin;Piriton;Chlorprophenpyridamine;but-2-enedioic acid; 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine;Chlorpheniramine maleate (JP14/USP);[3-(4-chlorophenyl)-3-pyridin-2-yl-propyl]-dimethyl-azanium; (Z)-4-hydroxy-4-oxo-but-2-enoate;Chlor-Tripolon;Neorestamin;Chlor-trimeton (TN);2-Pyridinepropanamine,?-(4-chlorophenyl)-N,- N-dimethyl-,(2Z)-2-butenedioate (1:1);chlorphenamine hydrogen maleate;Teldrin (TN); |
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CAS Number
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113-92-8 |
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Molecular Formula
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C20H23ClN2O4 |
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Molecular Weight
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390.867 |
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Density
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1.107 g/cm3 |
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Melting Point
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130-135 ºC |
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Boiling Point
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379 ºC at 760 mmHg |
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Flash Point
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183 ºC |
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HS CODE
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29333990 |
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PSA
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90.73000 |
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LogP
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3.53040 |
What is Chlorpheniramine maleate (113-92-8) used for?
Chlorpheniramine is a histamine H1 receptor antagonist with an IC75 value of 0.0016 μg/ml for reversal of histamine-induced spasms in isolated guinea pig ileum. It protects against intravenous histamine-induced death (PD50 = 0.15 mg/kg) and delays induction of aerosolized histamine-induced coughing (ED100sec = 0.44 mg/kg) in guinea pigs. Chlorpheniramine (20 mg/kg, i.p.) prevents histamine-induced passive cutaneous anaphylaxis (PCA) in rabbits. It also reduces respiratory resistance and hypersecretion of tracheobronchial fluid in a dog model of histamine-induced asthma. Formulations containing chlorpheniramine have been used in the treatment of seasonal allergies.
InChI:InChI=1/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)
Articles related to Chlorpheniramine maleate:
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Article
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Source
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| Simultaneous Determination of Acetaminophen, Caffeine, and Chlorphenamine Maleate in Paracetamol and Chlorphenamine Maleate Granules |
A simple and rapid HPLC method using phenacetin (PHN) as internal standard has been developed for simultaneous determination of acetaminophen, caffeine, and chlorphenamine maleate in the product compound paracetamol and chlorphenamine maleate granules. Separation and quantitation were achieved on a 250 mm × 4.6 mm, 5 μm particle, C18 column.
Sufang Sun, Guorui Liu & Yanhuan Wang
Chromatographia, Volume 64, pages 719–724, (2006)
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| Simultaneous High-Performance Liquid Chromatographic Determination of Paracetamol, Phenylephrine HCl, and Chlorpheniramine Maleate in Pharmaceutical Dosage Forms |
A rapid, precise, and specific high-performance liquid chromatographic method is described for the simultaneous determination of paracetamol, phenylephrine HCl, and chlorpheniramine maleate in combined pharmaceutical dosage forms. The method involves the use of a µBondapak CN RP analytical column (125 Å, 10 µm, 3.9 × 150 mm) at 22°C as the stationary phase with the mixture of acetonitrile and phosphate buffer (pH 6.22, 78:22) as the mobile phase. Derivatization of the drugs is not required.
Hamide Şenyuva, Tuncel Özden
Journal of Chromatographic Science, Volume 40, Issue 2, February 2002, Pages 97–100
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How to get the best price on Chlorpheniramine maleate?
Shanghai Wibson Biotechnology Co., Ltd. is a quality supplier and manufacturer of Chlorpheniramine maleate . You can buy high quality, low price Chlorpheniramine maleate 113-92-8 here. We have 16 years of experience in R&D and manufacturing, we have rich experience in shipping, many well-known companies have cooperated with us, and are good at shipping various chemical products with us.We can provide OEM,ODM service with low MOQ!
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