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CasNo: 197922-42-2
Molecular Formula: C164H252N44O55S
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Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue, designed to treat short bowel syndrome (SBS) in patients requiring parenteral nutrition. It enhances nutrient absorption by promoting intestinal growth and repair.
The CAS number of ALX 0600 is 197922-42-2.
More information of ALX 0600 197922-42-2 are:
Synonyms |
Gattex; Glucagon-like peptide II [2-glycine] (human); ALX 0600 |
CAS Number |
197922-42-2 |
Molecular Formula |
C164H252N44O55S |
Molecular Weight |
3752.13 |
PSA |
1649.52000 |
LogP |
1.01630 |
Approved for adults with SBS, teduglutide improves the absorption of fluids and nutrients by activating GLP-2 receptors in the gut, leading to increased intestinal villi height and crypt depth, thereby facilitating better digestive function and reducing reliance on IV nutrition. Teduglutide is synthesized using solid-phase peptide synthesis and produced via recombinant DNA technology in a modified strain of Escherichia coli. This method allows for the precise incorporation of amino acid modifications, specifically substituting glycine for alanine.
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